Invitrogen

FNIP2 Polyclonal Antibody

Name: FNIP2 Polyclonal Antibody
Brand: Invitrogen
SKU: PA5-20690

查看其他8个FNIP2抗体

说明书

实验方案

问题与答案

技术支持

说明书

实验方案

问题与答案

技术支持

说明书

实验方案

问题与答案

技术支持

抗体检测数据 (2)

FNIP2 Antibody in Immunohistochemistry (IHC)

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FNIP2 Antibody (PA5-20690) in IHC

Immunohistochemistry of FNIP2 in mouse skeletal muscle tissue with FNIP2 Polyclonal Antibody (Product # PA5-20690) at 5 µg/mL.

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Immunogen image

Immunogen Image FNIP2 Polyclonal Antibody

产品信息

PA5-20690

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1-2 µg/mL

免疫组化 (IHC)

5 µg/mL

产品规格

种属反应

Human, Mouse, Rat

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

A 16 amino acid peptide near the carboxy terminus of human FNIP2.

查看免疫原

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

1 mg/mL

纯化类型

Antigen affinity chromatography

保存液

PBS

内含物

0.02% sodium azide

保存条件

Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C

运输条件

Ambient (domestic); Wet ice (international)

AB_11157473

产品详细信息

A suggested positive control is rat skeletal muscle tissue lysate.

PA5-20690 can be used with blocking peptide PEP-0805.

靶标信息

FNIP2 is the second protein found to interact with folliculin, the product of the Birt-Hogg-Dube (BHD) gene. Folliculin is thought to act as a tumor suppressor as mutations or loss of heterozygosity in this gene are associated with BHD syndrome-related renal tumors. Folliculin and FNIP1, a protein that shares 49% identity to FNIP2, bind to AMPK, an important energy sensor in cells that negatively regulates the mammalian target of rapamycin (mTOR), a protein that is thought to be the master switch for cell growth and proliferation. FNIP1 and FNIP2 are able to form homo- and heteromeric multimers, suggesting these proteins may have a functional relationship.

仅用于科研。不用于诊断过程。未经明确授权不得转售。