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Product may be used with Sandwich ELISA (Recombinant protein).
Immunogen sequence: HHKTKPGPED KLHDQCSPWK KNACCTASTS QELHKDTSRL YNFNWDHCGK MEPACKRHFI QDTCLYECSP NLGPWIQQVN QTWRKERFLD VPL
FOLR2 is a member of the folate receptor (FOLR) family, and these genes exist in a cluster on chromosome 11. Members of this gene family have a high affinity for folic acid and for several reduced folic acid derivatives, and they mediate delivery of 5-methyltetrahydrofolate to the interior of cells. This protein has a 68% and 79% sequence homology with the FOLR1 and FOLR3 proteins, respectively. Although this protein was originally thought to be specific to placenta, it can also exist in other tissues, and it may play a role in the transport of methotrexate in synovial macrophages in rheumatoid arthritis patients.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: FBP; Folate receptor 2; folate receptor 2 (fetal); Folate receptor beta; folate receptor, beta; Folate receptor, fetal/placental; folate-binding protein, fetal/placental; FR-beta; Placental folate-binding protein
基因别名: BETA-HFR; FBP; FBP/PL-1; FOLR2; FR-BETA; FR-P3
UniProt ID: (Human) P14207
Entrez Gene ID: (Human) 2350