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Invitrogen
FOXA3 Polyclonal Antibody
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FOXA3 Antibody (PA5149600) in ChIP
ChIP Assay of FOXA3 in K562 cells. ChIP-Exo-Seq composite graph for FOXA3 polyclonal antibody (Product # PA5149600). Strand-specific reads (blue: forward, red: reverse) and IgG controls (black: forward, grey: reverse) are plotted against the distance from a composite set of reference binding sites. The antibody exhibits robust target enrichment compared to a non-specific IgG control and precisely reveals its structural organization around the binding site.
产品信息
PA5149600
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant protein corresponding to Human FOXA3
偶联物
形式
Liquid
浓度
0.1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: LGSVKMEAHD LAEWSYYPEA GEVYSPVTPV PTMAPLNSYM TLNPLSSPYP PGGLPASPLP SGP
Highest antigen sequence identity to the following orthologs: Mouse - 95%, Rat - 94%.
靶标信息
FOXA3 encodes a member of the forkhead class of DNA-binding proteins. These hepatocyte nuclear factors are transcriptional activators for liver-specific transcripts such as albumin and transthyretin, and they also interact with chromatin. Similar family members in mice have roles in the regulation of metabolism and in the differentiation of the pancreas and liver. The crystal structure of a similar protein in rat has been resolved.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Fork head-related protein FKH H3; Forkhead box protein A3; hepatocyte nuclear factor 3, gamma; Hepatocyte nuclear factor 3-gamma; HNF-3-gamma; HNF-3G; TCF-3G; Transcription factor 3G
基因别名: FKHH3; FOXA3; HNF3G; TCF3G
UniProt ID: (Human) P55318
Entrez Gene ID: (Human) 3171
RNA polymerase II transcription factor activity, sequence-specific DNA binding
transcription factor activity, sequence-specific DNA binding
transcription factor binding
protein domain specific binding
sequence-specific DNA binding
transcription regulatory region DNA binding
winged helix/forkhead transcription factor
