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Invitrogen
FOXM1 Polyclonal Antibody
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FOXM1 Antibody (PA5-95205) in WB
Western blot analysis of FOXM1 in Lane 1: HeLa whole cell lysate (40 µg), Lane 2: COLO320 whole cell lysate (40 µg), Lane 3: SW620 whole cell lysate (40 µg), Lane 4: SKOV whole cell lysate (40 µg), Lane 5: MCD-7 whole cell lysate (40 µg). Samples were incubated with FOXM1 polyclonal antibody (Product # PA5-95205).
产品信息
PA5-95205
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
E.coli-derived human FOXM1 recombinant protein (Position: A411-Q763).
偶联物
形式
Lyophilized
浓度
500 µg/mL
纯化类型
Affinity chromatography
保存液
PBS with 5mg BSA
内含物
0.05mg sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Human FOXM1 shares 75% and 76% amino acid (aa) sequences identity with mouse and rat FOXM1, respectively.
Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.
Positive Control - WB: human Hela whole cell, human COLO320 whole cell, human SW620 whole cell, human SKOV whole cell, human MCD-7 whole cell.|Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
靶标信息
FOXM1 (forkhead box protein M1) is a transcriptional factor regulating the expression of cell cycle genes essential for DNA replication and mitosis. FOXM1 plays a role in the control of cell proliferation and DNA break repairs participating in the DNA damage checkpoint response.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: FKH L16; FKHL 16; Forkhead box protein M1; Forkhead like 16; Forkhead, drosophila, homolog-like 16; Forkhead-related protein FKHL16; FOXM 1; FOXM 1c; Hepatocyte nuclear factor 3 forkhead homolog 11; HFH 11; HFH-11; HNF 3; HNF-3/fork-head homolog 11; HNF3; INS 1; INS1; M-phase phosphoprotein 2; MPHOSPH 2; MPM 2; MPM-2 reactive phosphoprotein 2; MPP 2; PIG 29; TGT3; Transcription factor Trident; Winged-helix factor from INS-1 cells
基因别名: FKHL16; FOXM1; FOXM1B; HFH-11; HFH11; HNF-3; INS-1; MPHOSPH2; MPP-2; MPP2; PIG29; TRIDENT; WIN
UniProt ID: (Human) Q08050
Entrez Gene ID: (Human) 2305
G2/M transition of mitotic cell cycle
negative regulation of transcription from RNA polymerase II promoter
DNA repair
transcription, DNA-templated
DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator
positive regulation of cell proliferation
negative regulation of stress-activated MAPK cascade
response to gonadotropin
negative regulation of transcription, DNA-templated
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
regulation of Ras protein signal transduction
response to cAMP
regulation of cell cycle
regulation of cell cycle arrest
negative regulation of cell aging
regulation of reactive oxygen species metabolic process
positive regulation of double-strand break repair
