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Invitrogen
FOXM1 Recombinant Rabbit Monoclonal Antibody (1H24L2)
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FOXM1 Antibody (702664) in ICC/IF
For immunofluorescence analysis, HCT 116 cells were fixed and permeabilized for detection of endogenous FOXM1 using Anti- FOXM1 Recombinant Rabbit Monoclonal Antibody (Product # 702664, 2 µg/mL) and labeled with Goat anti-Rabbit IgG (Heavy Chain) Superclonal™ Secondary Antibody, Alexa Fluor® 488 conjugate (Product # A27034, 1:2000). Panel a) shows representative cells that were stained for detection and localization of FOXM1 protein (green), Panel b) is stained for nuclei (blue) using SlowFade® Gold Antifade Mountant with DAPI (Product # S... View More
产品信息
702664
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
已发表种属
Human
宿主/亚型
Rabbit
/ IgG
Expression System
Expi293
分类
Recombinant Monoclonal
类型
Antibody
克隆号
1H24L2
抗原
Protein corresponding to human FOXM1 (aa1-aa250)
偶联物
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Protein A
保存液
PBS, pH 7.4
内含物
0.09% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
产品详细信息
This antibody is predicted to react with Monkey, Cat, and Pig.
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.
靶标信息
FOXM1 (forkhead box protein M1) is a transcriptional factor regulating the expression of cell cycle genes essential for DNA replication and mitosis. FOXM1 plays a role in the control of cell proliferation and DNA break repairs participating in the DNA damage checkpoint response.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: FKH L16; FKHL 16; Forkhead box protein M1; Forkhead like 16; Forkhead, drosophila, homolog-like 16; Forkhead-related protein FKHL16; FOXM 1; FOXM 1c; Hepatocyte nuclear factor 3 forkhead homolog 11; HFH 11; HFH-11; HNF 3; HNF-3/fork-head homolog 11; HNF3; INS 1; INS1; M-phase phosphoprotein 2; MPHOSPH 2; MPM 2; MPM-2 reactive phosphoprotein 2; MPP 2; PIG 29; TGT3; Transcription factor Trident; Winged-helix factor from INS-1 cells
基因别名: FKHL16; FOXM1; FOXM1B; HFH-11; HFH11; HNF-3; INS-1; MPHOSPH2; MPP-2; MPP2; PIG29; TRIDENT; WIN
UniProt ID: (Human) Q08050
Entrez Gene ID: (Human) 2305
G2/M transition of mitotic cell cycle
negative regulation of transcription from RNA polymerase II promoter
DNA repair
transcription, DNA-templated
DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator
positive regulation of cell proliferation
negative regulation of stress-activated MAPK cascade
response to gonadotropin
negative regulation of transcription, DNA-templated
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
regulation of Ras protein signal transduction
response to cAMP
regulation of cell cycle
regulation of cell cycle arrest
negative regulation of cell aging
regulation of reactive oxygen species metabolic process
positive regulation of double-strand break repair
