Invitrogen

FPR1 Polyclonal Antibody

Name: FPR1 Polyclonal Antibody
Brand: Invitrogen
SKU: PA5-33535

查看其他13个FPR1抗体

说明书

实验方案

问题与答案

技术支持

说明书

实验方案

问题与答案

技术支持

说明书

实验方案

问题与答案

技术支持

抗体检测数据 (1)

FPR1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

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FPR1 Antibody (PA5-33535) in IHC (P)

Immunohistochemistry analysis of FPR1 in human tonsil. Samples were incubated with FPR1 polyclonal antibody (Product # PA5-33535). Formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

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产品信息

PA5-33535

应用

建议稀释比

已发表文章

免疫组化（石蜡） (IHC (P))

2 µg/mL

产品规格

种属反应

Human

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

Synthetic 16 amino acid peptide from 2nd extracellular domain of human FPR1.

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

1 mg/mL

纯化类型

Antigen affinity chromatography

保存液

PBS

内含物

0.1% sodium azide

保存条件

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

运输条件

Ambient (domestic); Wet ice (international)

AB_2550915

产品详细信息

Percent identity with other species by BLAST analysis: Human (100%) Chimpanzee, Gorilla (94%) Orangutan (88%) Gibbon (81%).

靶标信息

FPR1 is a member of chemoattractant/chemokine GPCRs expressed mainly on leukocytes, neutrophils and monocytes. FPR1 is a seven transmembrane pertussis toxin-sensitive GPCR and binds to formylated peptides generated by bacteria resulting in leukocyte trafficking to the site of inflammation. Ligand binding to FPR results in activation of multiple effectors including phospholipase C leading to calcium mobilization and PKC activation. Other implications of FPR signaling include polarization of actin cytoskeleton, activation of various integrins, increased cell migration, phagocytosis, degranulation and release of reactive oxygen intermediates.

仅用于科研。不用于诊断过程。未经明确授权不得转售。