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Rockland
FREM2 Polyclonal Antibody
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FREM2 Antibody (600-401-BH2) in ICC/IF
Immunocytochemistry of FREM2 antibody. Tissue: A20 cells. Fixation: formalin fixed paraffin embedded. Antigen retrieval: not required. Primary antibody: FREM2 antibody at 20 µg/mL for 1 hr at RT. Secondary antibody: Peroxidase rabbit secondary antibody at 1:10,000 for 45 min at RT. Localization: FREM2 is a membrane protein. Staining: FREM2 as precipitated blue signal with pink nuclear counterstain.
产品信息
600-401-BH2
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Anti-FREM2 antibody was prepared from whole rabbit serum produced by repeated immunizations with a 19 amino acid synthetic peptide near the internal region of human FREM2.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Affinity chromatography
保存液
PBS, pH 7.2
内含物
0.02% sodium azide
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
靶标信息
FREM2 is a member of the FRAS1-related extracellular matrix protein family and like FREM1, mutations in the FREM2 gene are associated with Fraser syndrome. FREM2 localizes to the basement membrane, forming a ternary complex that plays a role in epidermal-dermal interactions during morphogenetic processes and is thought to be required for maintaining the integrity of the skin epithelium and the differentiated state of renal epithelia. The FREM2 gene is one of several genes whose transcription is affecteded by TFAP2C, a transcription factor involved in mammary development, differentiation, and oncogenesis.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: ECM3 homolog; FRAS1-related extracellular matrix protein 2; NV domain containing protein NV1; NV domain-containing protein 1
基因别名: 6030440P17Rik; 8430406N05Rik; b2b1562Clo; FREM2; Gm409; my; ne; Nv1
UniProt ID: (Human) Q5SZK8, (Mouse) Q6NVD0
Entrez Gene ID: (Human) 341640, (Mouse) 242022
