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Invitrogen
FRZB Polyclonal Antibody
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FRZB Antibody (PA5-117059) in WB
Western blot analysis of FRZB in rat spleen. Samples were incubated with FRZB Polyclonal antibody (Product # PA5-117059) using a dilution of 1:6,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-117059
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 166-325 of human FRZB (NP_0014542)
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
0.35 mg/mL
规格
35 µg
纯化类型
Affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Positive Samples: Mouse skeletal muscle
Immunogen sequence: SNGNCRGASS ERCKCKPIRA TQKTYFRNNY NYVIRAKVKE IKTKCHDVTA VVEVKEILKS SLVNIPRDTV NLYTSSGCLC PPLNVNEEYI IMGYEDEERS RLLLVEGSIA EKWKDRLGKK VKRWDMKLRH LGLSKSDSSN SDSTQSQKSG RNSNPRQARN
靶标信息
The protein encoded by this gene is a secreted protein that is involved in the regulation of bone development. Defects in this gene are a cause of female-specific osteoarthritis (OA) susceptibility.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: FREOS1; Frezzled; Fritz; Frizzled-related protein 1; FrzB-1; FRZB1sFRP-3; Secreted frizzled-related protein 3; secreted frizzled-related sequence protein 3; sFRP-3; SFRP3frezzled
基因别名: FIZ; FRE; frezzled; fritz; FRP; FRZB; frzb-1; FRZB1; SFRP3
UniProt ID: (Mouse) P97401
Entrez Gene ID: (Mouse) 20378
multicellular organism development
negative regulation of cell proliferation
negative regulation of cell development
Wnt signaling pathway
cell differentiation
negative regulation of Wnt signaling pathway
negative regulation of cell growth
non-canonical Wnt signaling pathway
inner ear morphogenesis
positive regulation of apoptotic process
positive regulation of fat cell differentiation
convergent extension involved in organogenesis
canonical Wnt signaling pathway
negative regulation of cartilage development
negative regulation of hepatocyte differentiation
negative regulation of canonical Wnt signaling pathway
cochlea morphogenesis
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