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Abnova
FRZB Monoclonal Antibody (1H8)
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产品信息
H00002487-M05
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG2a, kappa
分类
Monoclonal
类型
Antibody
克隆号
1H8
抗原
FRZB (NP_001454, 102 a.a. approximately 190 a.a) full length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
偶联物
形式
Liquid
浓度
See Label
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Sequence of this protein is as follows: HEPIKPCKSV CERARQGCEP ILIKYRHSWP ENLACEELPV YDRGVCISPE AIVTADGADF PMDSSNGNCR GASSERCKCK PIRATQKTY*
靶标信息
The protein encoded by this gene is a secreted protein that is involved in the regulation of bone development. Defects in this gene are a cause of female-specific osteoarthritis (OA) susceptibility.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: FREOS1; Frezzled; Fritz; frizzled homolog-related; Frizzled-related protein 1; FrzB-1; FRZB1sFRP-3; Secreted frizzled-related protein 3; sFRP-3; SFRP3frezzled
基因别名: FIZ; FRE; FRITZ; FRP; FRP-3; FRZB; FRZB-1; FRZB-PEN; FRZB1; FZRB; hFIZ; OS1; SFRP3; SRFP3
UniProt ID: (Human) Q92765
Entrez Gene ID: (Human) 2487
skeletal system development
G-protein coupled receptor signaling pathway
negative regulation of cell proliferation
negative regulation of cell development
neural crest cell differentiation
negative regulation of Wnt signaling pathway
negative regulation of cell growth
non-canonical Wnt signaling pathway
positive regulation of apoptotic process
positive regulation of fat cell differentiation
convergent extension involved in organogenesis
negative regulation of cartilage development
somite development
negative regulation of hepatocyte differentiation
negative regulation of canonical Wnt signaling pathway
cochlea morphogenesis
