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Invitrogen
FUK Polyclonal Antibody
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FUK Antibody (PA5-120540) in WB
Western blot analysis of FUK in extracts of various cell lines. Samples were incubated with FUK Polyclonal antibody (Product # PA5-120540) using a dilution of 1:3,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 30s.
产品信息
PA5-120540
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 795-1084 of human FUK (NP_659496.2).
偶联物
形式
Liquid
浓度
2.3 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.01% thimerosal
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Positive test controls include: U-87MG, Mouse brain, Mouse kidney.
Immunogen sequence: LLKAAFICAG IVHVHSELQL SEQLLRTFGG GFELHTWSEL PHGSGLGTSS ILAGTALAAL QRAAGRVVGT EALIHAVLHL EQVLTTGGGW QDQVGGLMPG IKVGRSRAQL PLKVEVEEVT VPEGFVQKLN DHLLLVYTGK TRLARNLLQD VLRSWYARLP AVVQNAHSLV RQTEECAEGF RQGSLPLLGQ CLTSYWEQKK LMAPGCEPLT VRRMMDVLAP HVHGQSLAGA GGGGFLYLLT KEPQQKEALE AVLAKTEGLG NYSIHLVEVD TQGLSLKLLG TEASTCCPFP
靶标信息
The protein encoded by this gene belongs to the GHMP (galacto-, homoserine, mevalonate and phosphomevalonate) kinase family and catalyzes the phosphorylation of L-fucose to form beta-L-fucose 1-phosphate. This enzyme catalyzes the first step in the utilization of free L-fucose in glycoprotein and glycolipid synthesis. L-fucose may be important in mediating a number of cell-cell interactions such as blood group antigen recognition, inflammation, and metastatis. While several transcript variants may exist for this gene, the full-length nature of only one has been described to date.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Fucokinase; L-fucose kinase; mFLJ00241 protein; UNQ5838
基因别名: 1110046B12Rik; AI303278; FCSK; FUK
UniProt ID: (Human) Q8N0W3, (Mouse) Q7TMC8
Entrez Gene ID: (Human) 197258, (Mouse) 234730
