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Immunogen sequence: HCMAENVTRE DFLVGRPPEL GQGDADVAGY LQSARAQLWR ELRDQPLTMA YVSSGSYSYM TSSASEFLLS LTLPGAPGAQ IVHSQV
Highest antigen sequence identity to the following orthologs: Mouse - 73%, Rat - 71%.
The protein encoded by this gene belongs to the GHMP (galacto-, homoserine, mevalonate and phosphomevalonate) kinase family and catalyzes the phosphorylation of L-fucose to form beta-L-fucose 1-phosphate. This enzyme catalyzes the first step in the utilization of free L-fucose in glycoprotein and glycolipid synthesis. L-fucose may be important in mediating a number of cell-cell interactions such as blood group antigen recognition, inflammation, and metastatis. While several transcript variants may exist for this gene, the full-length nature of only one has been described to date.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Fucokinase; L-fucose kinase; UNQ5838
基因别名: 1110046B12Rik; FCSK; FUK
UniProt ID: (Human) Q8N0W3
Entrez Gene ID: (Human) 197258
分子生物学功能: kinase transferase metabolite interconversion enzyme