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Invitrogen
FUS Polyclonal Antibody
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FUS Antibody (PA5-79286) in WB
Western blot was performed using Anti-FUS Polyclonal Antibody(Product # PA5-79286) and a 70kDa band corresponding to FUS was observed across all the tested cell lines and tissues. Nuclear enriched extracts (30 µg lysate) of NTERA-2 cl.D1 (Lane 1), NIH:OVCAR-3 (Lane 2), U-2 OS (Lane 3), MCF7 (Lane 4), HeLa (Lane 5), A-431 (Lane 6), HEK-293 (Lane 7), Mouse Brain (Lane 8), Mouse Uterus (Lane 9), Mouse Pancreas (Lane 10), Rat Brain (Lane 11) were electrophoresed using NuPAGE™ 10% Bis-Tris Protein Gel (Product # NP0302BOX). Resolved proteins we... View More
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-79286
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthetic peptide corresponding to a sequence of human TLS / FUS (DNNTIFVQGLGENVTIESVADYFKQIGIIKTNKKT).
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Lyophilized
浓度
500 µg/mL
规格
100 µg
纯化类型
Antigen affinity chromatography
保存液
PBS with 4mg trehalose
内含物
0.05mg sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.
Positive Control - WB: human HepG2 whole cell, human K562 whole cell, mouse NIH3T3 whole cell.
靶标信息
This gene encodes a multifunctional protein component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complex. The hnRNP complex is involved in pre-mRNA splicing and the export of fully processed mRNA to the cytoplasm. This protein belongs to the FET family of RNA-binding proteins which have been implicated in cellular processes that include regulation of gene expression, maintenance of genomic integrity and mRNA/microRNA processing. Alternative splicing results in multiple transcript variants. Defects in this gene result in amyotrophic lateral sclerosis type 6.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: 16) in malignant liposarcoma); 16) malignant liposarcoma; 75 kDa DNA-pairing protein; fusion (involved in t(12; fusion, derived from t(12; fusion, derived from t(12;16) malignant liposarcoma; hnRNP P2; Oncogene FUS; Oncogene TLS; pigpen protein; POMp75; Protein pigpen; RNA-binding protein FUS; translocated in liposarcoma; Translocated in liposarcoma protein
基因别名: D430004D17Rik; D930039C12Rik; FUS; Fus1; TLS
UniProt ID: (Mouse) P56959
Entrez Gene ID: (Rat) 317385, (Mouse) 233908
nucleotide binding
zinc ion binding
estrogen receptor binding
myosin V binding
ionotropic glutamate receptor binding
identical protein binding
poly(A) RNA binding
retinoid X receptor binding
thyroid hormone receptor binding
nucleic acid binding
DNA binding
RNA binding
metal ion binding
RNA metabolism protein
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Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
