Abnova

FUSIP1 Monoclonal Antibody (1G11)

Name: FUSIP1 Monoclonal Antibody (1G11)
Brand: Abnova
SKU: H00010772-M07
Price: 6404.00 CNY
Availability: InStock

查看其他7个SRSF10抗体

说明书

Certificates

实验方案

问题与答案

技术支持

说明书

Certificates

实验方案

问题与答案

技术支持

说明书

Certificates

实验方案

问题与答案

技术支持

Additional Information:

抗体检测数据 (1)

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FUSIP1 Antibody (H00010772-M07) in WB

FUSIP1 monoclonal antibody (M07), clone 1G11. Western Blot analysis of FUSIP1 expression in Jurkat.

Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.

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产品信息

H00010772-M07

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1-5 µg/mL

免疫细胞化学 (ICC/IF)

10-100 µg/mL

酶联免疫吸附实验 (ELISA)

10 µg/mL

产品规格

种属反应

Human

宿主/亚型

Mouse / IgG1, kappa

分类

Monoclonal

类型

Antibody

克隆号

1G11

抗原

FUSIP1 (AAH05039, 1 a.a. approximately 100 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

0.5 mg/mL

100 µg

纯化类型

Protein A

保存液

PBS, pH 7.4

内含物

no preservative

保存条件

-20°C, Avoid Freeze/Thaw Cycles

Ambient (domestic); Wet ice (international)

产品详细信息

Product may be used with Western Blot (Cell lysate).

Immunogen sequence: MSRYLRPPNT SLFVRNVADD TRSEDLRREF GRYGPIVDVY VPLDFYTRRP RGFAYVQFED VRDAEDALHN LDRKWICGRQ IEIQFAQGDR KTPNQMKAKE

靶标信息

SRSF10 (Serine and Arginine Rich Splicing Factor 10) is a member of the SR family of RNA-binding proteins that regulates alternative pre-mRNA splicing. It contains an RNA recognition motif (RRM) and a serine/arginine-rich (RS) domain that mediates RNA binding and protein-protein interactions within the spliceosome. SRSF10 functions as a context-dependent splicing regulator, capable of promoting or repressing exon inclusion depending on cellular conditions. Notably, it undergoes phosphorylation-dependent regulation, and during cellular stress or mitosis it can shift from an activator to a repressor of splicing. SRSF10 has been implicated in cell cycle control, apoptosis, metabolic regulation, and cancer-associated splicing alterations. Formerly known as FUSIP1 (FUS-interacting protein 1), SRSF10 is widely studied for its role in dynamic and stress-responsive RNA processing.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

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Cite this product

生物信息学

蛋白别名: 40 kDa SR-repressor protein; contains RNP1 and RNP2 motifs; RS domain; FUS interacting protein (serine-arginine rich) 1; FUS-interacting protein (serine-arginine rich) 2; neural-salient SR protein; protein phosphatase 1, regulatory subunit 149; serine-arginine repressor protein (40 kDa); splicing factor; splicing factor SRp38; splicing factor, arginine/serine-rich 13; splicing factor, arginine/serine-rich 13A; SR protein; SR splicing factor 10; TLS-associated protein TASR; TLS-associated protein with Ser-Arg repeats; TLS-associated protein with SR repeats; TLS-associated serine-arginine protein 1; TLS-associated serine-arginine protein 2; TLS-associated SR protein; unnamed protein product

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基因别名: FUSIP1; FUSIP2; NSSR; PPP1R149; SFRS13; SFRS13A; SRp38; SRrp40; TASR; TASR1; TASR2

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UniProt ID: (Human) O75494

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Entrez Gene ID: (Human) 10772

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功能

nucleic acid binding RNA binding mRNA binding protein binding RS domain binding

参与通路

spliceosomal tri-snRNP complex assembly RNA splicing, via transesterification reactions regulation of alternative mRNA splicing, via spliceosome mRNA splicing, via spliceosome regulation of transcription, DNA-templated mRNA splice site selection cytosolic transport regulation of mRNA splicing, via spliceosome negative regulation of mRNA splicing, via spliceosome