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Abnova
FUT4 Monoclonal Antibody (8B2)
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
H00002526-M01
产品规格
种属反应
Human,
Rat
宿主/亚型
Mouse
/ IgG2a, kappa
分类
Monoclonal
类型
Antibody
克隆号
8B2
抗原
FUT4 (NP_002024.1, 167 a.a. approximately 265 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
0.31 mg/mL
规格
100 µg
纯化类型
Protein A
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Product may be used with Western Blot (Cell lysate).
Immunogen sequence: ITYACWGQLP PLPWASPTPS RPVGVLLWWE PFGGRDSAPR PPPDCRLRFN ISGCRLLTDR ASYGEAQAVL FHHRDLVKGP PDWPPPWGIQ AHTAEEVDL
靶标信息
FUT4 (Fucosyltransferase 4) is a Protein Coding gene. Diseases associated with FUT4 include Colon Adenocarcinoma and Liver Lymphoma. Among its related pathways are Glycosphingolipid biosynthesis - lacto and neolacto series and Mannose type O-glycan biosynthesis. Gene Ontology (GO) annotations related to this gene include fucosyltransferase activity and alpha-(1->3)-fucosyltransferase activity. The product of this gene transfers fucose to N-acetyllactosamine polysaccharides to generate fucosylated carbohydrate structures. It catalyzes the synthesis of the non-sialylated antigen, Lewis x (CD15).
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: 4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase; alpha (1,3) fucosyltransferase, myeloid-specific; alpha 1,3-fucosyltransferase Fuc-T (similar to mouse Fut4); alpha 13-fucosyltransferase Fuc-T (similar to mouse Fut4); ELAM ligand fucosyltransferase; ELAM-1 ligand fucosyltransferase; fuc-TIV; fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific); fucosyltransferase IV; fucT-IV; galactoside 3-L-fucosyltransferase; Lewis X; stage-specific embryonic antigen 1
基因别名: CD15; ELFT; FCT3A; FUC-TIV; Fuct; FUTIV; LeX; SSEA-1
UniProt ID: (Human) P22083
Entrez Gene ID: (Human) 2526, (Rat) 60670
carbohydrate metabolic process
protein N-linked glycosylation
protein O-linked glycosylation
sphingolipid metabolic process
glycosphingolipid biosynthetic process
glycoprotein biosynthetic process
oligosaccharide metabolic process
oligosaccharide biosynthetic process
L-fucose catabolic process
lymphocyte migration into lymph node
Lewis x epitope biosynthetic process
positive regulation of neutrophil migration
regulation of leukocyte cell-cell adhesion
positive regulation of leukocyte tethering or rolling
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