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          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

          • Primary Antibodies ›
          • FXN Antibodies

          Abnova

          FXN Monoclonal Antibody (3E7)

          查看其他24个FXN抗体

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          Cite FXN Monoclonal Antibody (3E7)

          • 抗体检测数据 (1)
          FXN Antibody in ELISA (ELISA)
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          FXN Antibody in ELISA (ELISA)
          Group 53 Created with Sketch.

          图: 1 / 1

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          FXN Antibody (H00002395-M05) in ELISA

          Detection limit for recombinant GST tagged FXN is approximately 0.03 ng/mL as a capture antibody. {{ $ctrl.currentElement.advancedVerification.fullName }} 验证信息 View more
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          查看产品

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          FXN Antibody in ELISA (ELISA)
          FXN Monoclonal Antibody (3E7)

          产品信息

          H00002395-M05

          应用
          建议稀释比
          已发表文章

          免疫印迹 (WB)

          1-5 µg/mL
          -

          酶联免疫吸附实验 (ELISA)

          0.03 ng/mL
          -
          产品规格

          种属反应

          Human

          宿主/亚型

          Mouse / IgG1, kappa

          分类

          Monoclonal

          类型

          Antibody

          克隆号

          3E7

          抗原

          FXN (AAH48097.1, 91 a.a. approximately 200 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
          查看免疫原

          偶联物

          Unconjugated Unconjugated Unconjugated

          形式

          Liquid

          浓度

          See Label

          纯化类型

          Affinity chromatography

          保存液

          PBS, pH 7.4

          内含物

          no preservative

          保存条件

          -20°C, Avoid Freeze/Thaw Cycles

          运输条件

          Ambient (domestic); Wet ice (international)

          产品详细信息

          Sequence of this protein is as follows: DETTYERLAE ETLDSLAEFF EDLADKPYTF EDYDVSFGSG VLTVKLGGDL GTYVINKQTP NKQIWLSSPS SGPKRYDWTG KNWVYSHDGV SLHELLAAEL TKALKTKLDL

          靶标信息

          FXN is a mitochondrial protein which belongs to the FRATAXIN family. The protein functions in regulating mitochondrial iron transport and respiration. The expansion of intronic trinucleotide repeat GAA results in Friedreich ataxia.

          仅用于科研。不用于诊断过程。未经明确授权不得转售。

          篇参考文献 (0)

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          引用该产品

          生物信息学

          蛋白别名: Frataxin, mitochondrial; Friedreich ataxia protein; Fxn

          查看更多 收起

          基因别名: CyaY; FA; FARR; FRDA; FXN; X25

          查看更多 收起

          UniProt ID: (Human) Q16595

          查看更多 收起

          Entrez Gene ID: (Human) 2395

          查看更多 收起

          功能
          ferroxidase activity protein binding ferrous iron binding ferric iron binding iron chaperone activity iron-sulfur cluster binding 2 iron, 2 sulfur cluster binding transfer/carrier protein
          参与通路
          oxidative phosphorylation heme biosynthetic process ion transport cellular iron ion homeostasis mitochondrion organization adult walking behavior positive regulation of cell proliferation aerobic respiration embryo development ending in birth or egg hatching response to iron ion regulation of ferrochelatase activity protein autoprocessing iron incorporation into metallo-sulfur cluster proprioception positive regulation of cell growth negative regulation of multicellular organism growth negative regulation of apoptotic process positive regulation of catalytic activity small molecule metabolic process negative regulation of organ growth positive regulation of lyase activity cellular response to hydrogen peroxide negative regulation of release of cytochrome c from mitochondria positive regulation of succinate dehydrogenase activity positive regulation of aconitate hydratase activity
          It has to be done as per old AB suggested Products section.
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          性能保障

          只要您发现Invitrogen抗体在实验中的表现与网站或说明书的所述内容不符,您即可享受免费退换货服务。*

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