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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Antibody detects endogenous levels of total FXYD2.
The human FXYD2 (pronounced fix-id) gene maps to chromosome 11q23 and encodes the gamma subunit of Na/K-ATPase (NKA). FXYD2 gamma subunit modulates NKA activity by inducing ion channel activity. The mammalian FXYD family maintains Na+ and K+ gradients between the intracellular and extracellular milieus of cells in processes such as renal Na+-reabsorption, muscle contraction and neuronal excitability. FXYDs are single-span membrane proteins that share a 35 amino acid signature domain, beginning with the sequence PFXYD and containing 7 invariant and 6 conserved amino acids. Other members of the FXYD family include FXYD1 (PLM, phospholemman), FXYD3 (Mat8, mammary tumor protein 8), FXYD4 (CHIF) and FXYD5 (RIC).
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: ATPase, Na+/K+ transporting, gamma 1 polypeptide; FXYD domain-containing ion transport regulator 2; Na(+)/K(+) ATPase subunit gamma; regulator 2; Sodium Potassium ATPase; Sodium pump gamma chain; sodium/potassium-transporting ATPase gamma chain; Sodium/potassium-transporting ATPase subunit gamma
基因别名: ATP1C; ATP1G1; FXYD2
UniProt ID: (Mouse) Q04646
Entrez Gene ID: (Mouse) 11936