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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
The human FXYD2 (pronounced fix-id) gene maps to chromosome 11q23 and encodes the gamma subunit of Na/K-ATPase (NKA). FXYD2 gamma subunit modulates NKA activity by inducing ion channel activity. The mammalian FXYD family maintains Na+ and K+ gradients between the intracellular and extracellular milieus of cells in processes such as renal Na+-reabsorption, muscle contraction and neuronal excitability. FXYDs are single-span membrane proteins that share a 35 amino acid signature domain, beginning with the sequence PFXYD and containing 7 invariant and 6 conserved amino acids. Other members of the FXYD family include FXYD1 (PLM, phospholemman), FXYD3 (Mat8, mammary tumor protein 8), FXYD4 (CHIF) and FXYD5 (RIC).
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: FXYD domain-containing ion transport regulator 2; Na(+)/K(+) ATPase subunit gamma; regulator 2; Sodium Potassium ATPase; Sodium pump gamma chain; Sodium/potassium-transporting ATPase subunit gamma
基因别名: ATP1C; ATP1G1; FXYD2
Entrez Gene ID: (Human) 486