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Invitrogen
FZD5 Monoclonal Antibody (2D12)
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产品信息
MA5-17080
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
已发表种属
C. elegans
宿主/亚型
Mouse
/ IgG1
分类
Monoclonal
类型
Antibody
克隆号
2D12
抗原
Purified recombinant fragment of human FZD5 (amino acids:151-217) expressed in E. Coli.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein G
保存液
PBS
内含物
0.05% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
MA5-17080 targets FZD5 in FACS, indirect ELISA, and WB applications and shows reactivity with Human samples.
The MA5-17080 immunogen is purified recombinant fragment of human FZD5 (amino acids:151-217) expressed in E. Coli.
MA5-17080 detects FZD5 which has a predicted molecular weight of approximately 64.5kDa.
靶标信息
Members of the 'frizzled' gene family encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The FZD5 protein is believed to be the receptor for the Wnt5A ligand.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: DKFZp434E2135; frizzled 5, seven transmembrane spanning receptor; frizzled family receptor 5; Frizzled-5; Fz-5; Fz5; Fzd-5; FzE5; MGC129692; seven-transmembrane receptor frizzled-5; Wnt receptor
基因别名: C2orf31; FZD5; HFZ5
UniProt ID: (Human) Q13467
Entrez Gene ID: (Human) 7855
embryonic axis specification
angiogenesis
positive regulation of T cell cytokine production
G-protein coupled receptor signaling pathway
Wnt signaling pathway, calcium modulating pathway
synapse assembly
negative regulation of cell proliferation
anterior/posterior axis specification, embryo
neuron differentiation
post-embryonic camera-type eye development
positive regulation of interferon-gamma production
T cell differentiation in thymus
non-canonical Wnt signaling pathway
positive regulation of JUN kinase activity
Wnt signaling pathway involved in dorsal/ventral axis specification
positive regulation of transcription from RNA polymerase II promoter
cell maturation
embryonic camera-type eye morphogenesis
Spemann organizer formation
canonical Wnt signaling pathway
Wnt signaling pathway, planar cell polarity pathway
apoptotic process involved in morphogenesis
branching involved in labyrinthine layer morphogenesis
syncytiotrophoblast cell differentiation involved in labyrinthine layer development
labyrinthine layer blood vessel development
chorionic trophoblast cell differentiation
regulation of canonical Wnt signaling pathway
cellular response to molecule of bacterial origin
regulation of chorionic trophoblast cell proliferation
regulation of mitophagy
positive regulation of protein targeting to mitochondrion
beta-catenin destruction complex disassembly
regulation of bicellular tight junction assembly
