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Invitrogen
Factor D Polyclonal Antibody
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Factor D Antibody (PA5-79034) in IHC (P)
Immunohistochemistry (Paraffin) analysis of Factor D in paraffin-embedded section of human pancreatic cancer tissue using Factor D Polyclonal Antibody (Product # PA5-79034). Heat mediated antigen retrieval was performed in EDTA buffer (pH 8.0, epitope retrieval solution). The tissue section was blocked with 10% goat serum. The tissue section was then incubated with the primary antibody at a 2 µg/mL dilution... View More
产品信息
PA5-79034
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
已发表种属
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
E. coli-derived human Factor D recombinant protein (Position: I26-A253).
偶联物
形式
Lyophilized
浓度
500 µg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS with 4mg trehalose
内含物
no preservative
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.
Positive Control - WB: human THP-1 whole cell, human Hela whole cell, rat lung tissue, mouse lung tissue, mouse NIH/3T3 whole cell. IHC: human pancreatic cancer tissue, human breast cancer tissue, mouse adipose tissue, rat kidney tissue.
靶标信息
Complement factor D is a serine protease of the alternative pathway of complement activation. The protein is a single chain polypeptide with a molecular mass of 25 kDa. Factor D cleaves factor B bound to C3b, generating the alternative pathway C3 convertase C3bBb and releasing the Ba fragment.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: 28 kDa adipocyte protein; Adipsin; C3 convertase activator; Complement factor D; complement factor D (adipsin); complement factor D preproprotein; D component (adipsin) of complement; D component of complement (adipsin); EC 3.4.21.46; Endogenous vascular elastase; Properdin factor D
基因别名: ADIPSIN; ADN; CFD; DF; EVE; PFD
UniProt ID: (Human) P00746, (Rat) P32038, (Mouse) P03953
Entrez Gene ID: (Human) 1675, (Rat) 54249, (Mouse) 11537
