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Invitrogen
Fascin Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-82210
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
0.10 mg/mL
规格
10 µg
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: GKDELFALEQ SCAQVVLQAA NERNVSTRQG MDLSANQDEE TDQETFQLEI DRDTKKCAFR THTGKYWTLT ATGGVQSTAS SKNASCYFDI EWRDRRITLR ASNGKFVTSK KNGQ
Highest antigen sequence indentity to the following orthologs: Mouse - 96%, Rat - 63%.
靶标信息
Fascin organizes filamentous actin into bundles with a minimum of 4. 1:1 actin/fascin ratio. It is probably involved in the assembly of actin filament bundles present in microspikes, membrane ruffles, and stress fibers.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: 55 kDa actin-bundling protein; 55kDa actin-bundling protein; epididymis secretory sperm binding protein; fascin 1; Fascin homolog 1; fascin homolog 1, actin bundling protein; fascin homolog 1, actin-bundling protein; fascin-like protein; BLES06; Fascin1; Singed; Singed (Drosophila) like (sea urchin fascin homolog like); singed-like (fascin homolog, sea urchin); singed-like protein; unnamed protein product
基因别名: Fan1; Fascin; fascin-1; HSN; p55; SNL
UniProt ID: (Human) Q16658, (Mouse) Q61553, (Rat) P85845
Entrez Gene ID: (Human) 6624, (Mouse) 14086, (Rat) 683788
actin filament organization
cell-cell junction assembly
establishment or maintenance of cell polarity
positive regulation of lamellipodium assembly
cell migration
microspike assembly
actin cytoskeleton organization
parallel actin filament bundle assembly
regulation of microvillus assembly
regulation of actin cytoskeleton organization
establishment of apical/basal cell polarity
cell motility
actin filament bundle assembly
positive regulation of filopodium assembly
positive regulation of podosome assembly
positive regulation of extracellular matrix disassembly
liver development
cellular response to cell-matrix adhesion
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
