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Invitrogen
Fascin Polyclonal Antibody
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Fascin Antibody (PA5-95016) in WB
Western blot analysis of Fascin in Lane 1: U87 whole cell lysate (40 µg), Lane 2: A549 whole cell lysate (40 µg), Lane 3: MCF-7 whole cell lysate (40 µg), Lane 4: HT1080 whole cell lysate (40 µg). Samples were incubated with Fascin polyclonal antibody (Product # PA5-95016).
产品信息
PA5-95016
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthetic peptide corresponding to a sequence at the N-terminus of human Fascin (97-113aa DDGRWSLQSEAHRRYFG).
偶联物
形式
Lyophilized
浓度
500 µg/mL
纯化类型
Affinity chromatography
保存液
PBS with 5mg BSA
内含物
0.05mg sodium azide, 0.05mg thimerosal
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.
Positive Control - WB: U87 whole cell, A549 whole cell, MCF-7 whole cell, HT1080 whole cell.|Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
靶标信息
Fascin organizes filamentous actin into bundles with a minimum of 4. 1:1 actin/fascin ratio. It is probably involved in the assembly of actin filament bundles present in microspikes, membrane ruffles, and stress fibers.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: 55 kDa actin-bundling protein; 55kDa actin-bundling protein; Fascin; fascin 1; Fascin homolog 1; fascin homolog 1, actin bundling protein; fascin homolog 1, actin-bundling protein; Fascin1; fscn1 {ECO:0000250|UniProtKB:Q16658}; p55; Singed; Singed (Drosophila) like (sea urchin fascin homolog like); singed-like (fascin homolog, sea urchin); Singed-like protein
基因别名: AI663989; FAN1; Fascin; fascin-1; FSCN1; HSN; p55; SNL
UniProt ID: (Human) Q16658, (Rat) P85845, (Mouse) Q61553
Entrez Gene ID: (Human) 6624, (Rat) 683788, (Mouse) 14086
cell-cell junction assembly
cell proliferation
anatomical structure morphogenesis
positive regulation of lamellipodium assembly
cell migration
microspike assembly
actin cytoskeleton organization
regulation of microvillus assembly
regulation of actin cytoskeleton organization
establishment of apical/basal cell polarity
cell motility
actin filament bundle assembly
positive regulation of filopodium assembly
positive regulation of podosome assembly
positive regulation of extracellular matrix disassembly
cell-cell adhesion
liver development
cellular response to cell-matrix adhesion
actin filament organization
