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Invitrogen
Fascin Monoclonal Antibody (55K2)
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Fascin Antibody (MA5-47716) in ICC/IF
Immunocytochemistry analysis of Fascin in aldehyde fixed and NP-40 permeabilized human NCI-H1915 lung carcinoma cells. The cells were labeled with mouse Fascin monoclonal antibody (Product # MA5-47716). The antibody was detected using goat anti-mouse DyLight® 594.
产品信息
MA5-47716
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Mouse
/ IgG1
分类
Monoclonal
类型
Antibody
克隆号
55K2
抗原
Clone (55K2) was generated from full-length human fascin purified from HeLa cells. This sequence has high homology to rat and mouse fascin.
偶联物
形式
Liquid
浓度
0.25 mg/mL
纯化类型
Protein A
保存液
PBS with 1mg/mL BSA, 50% glycerol
内含物
0.05% sodium azide
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
The antibody detects a 55 kDa* band corresponding to fascin on SDS-PAGE immunoblots of human A431 and HeLa, as well as mouse C2C12 and rat PC12.
靶标信息
Fascin organizes filamentous actin into bundles with a minimum of 4. 1:1 actin/fascin ratio. It is probably involved in the assembly of actin filament bundles present in microspikes, membrane ruffles, and stress fibers.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: 55 kDa actin-bundling protein; 55kDa actin-bundling protein; Fascin; fascin 1; Fascin homolog 1; fascin homolog 1, actin bundling protein; fascin homolog 1, actin-bundling protein; Fascin1; fscn1 {ECO:0000250|UniProtKB:Q16658}; p55; Singed; Singed (Drosophila) like (sea urchin fascin homolog like); singed-like (fascin homolog, sea urchin); Singed-like protein
基因别名: AI663989; FAN1; Fascin; fascin-1; FSCN1; HSN; p55; SNL
UniProt ID: (Human) Q16658, (Rat) P85845, (Mouse) Q61553
Entrez Gene ID: (Human) 6624, (Rat) 683788, (Mouse) 14086
cell-cell junction assembly
cell proliferation
anatomical structure morphogenesis
positive regulation of lamellipodium assembly
cell migration
microspike assembly
actin cytoskeleton organization
regulation of microvillus assembly
regulation of actin cytoskeleton organization
establishment of apical/basal cell polarity
cell motility
actin filament bundle assembly
positive regulation of filopodium assembly
positive regulation of podosome assembly
positive regulation of extracellular matrix disassembly
cell-cell adhesion
liver development
cellular response to cell-matrix adhesion
actin filament organization
