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Invitrogen
Fenthion Recombinant Mouse Monoclonal Antibody (1A6)
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Fenthion Antibody (MA566501) in SDS-PAGE
SDS-PAGE characterization of Fenthion under reducing conditions. Lane M: Protein marker (kDa); Lane FNT: Purified Fenthion Recombinant Monoclonal (Product # MA566501). Fenthion showing heavy chain (~50 kDa) and light chain (~25 kDa). Gels were stained with Coomassie Brilliant Blue R-550.
产品信息
MA566501
产品规格
种属反应
Chemical
宿主/亚型
Mouse
/ IgG
Expression System
CHO cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
1A6
抗原
Conjugate of FNT hapten and KLH.
偶联物
形式
Liquid
浓度
10 mg/mL
纯化类型
Protein G
保存液
PBS
内含物
0.09% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
靶标信息
Fenthion is an organophosphate insecticide that undergoes metabolic transformation primarily through the action of flavin-containing monooxygenase 1 (FMO1), which catalyzes its oxidation to fenthion sulfoxide in a stereoselective manner. The gene expression related to DNA repair pathways, such as Rad18 and Xrcc2, is affected by fenthion exposure, indicating its potential genotoxic effects. Fenthion and its metabolites, including fenthion oxon, fenthion oxon sulfoxide, and fenthion sulfone, can be analyzed using ultra-high performance liquid chromatography-tandem mass spectrometry. The molecular structure of fenthion and its derivatives is crucial for understanding their biochemical interactions and environmental impact. The degradation pathways of fenthion involve complex interactions with various precursor species, highlighting the importance of studying its environmental fate and toxicity.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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