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SLC40A1 is an iron-regulated transporter assumed to play roles in intestinal iron absorption and cellular iron release. It mediates iron efflux in the presence of ferroxidase. Defects in SLC40A1 cause hemochromatosis type 4 (HFE4), which is an autosomal dominant iron-loading disorder.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Ferroportin; Ferroportin-1; iron regulated gene 1; Iron-regulated transporter 1; solute carrier family 11 (proton-coupled divalent metal ion transporters), member 3; solute carrier family 40 (iron-regulated transporter), member 1; Solute carrier family 40 member 1
基因别名: FPN; FPN1; HFE4; IREG1; MST079; MSTP079; MTP1; SLC11A3; SLC40A1
UniProt ID: (Human) Q9NP59
Entrez Gene ID: (Human) 30061