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Invitrogen
Fibulin 3 Recombinant Rabbit Monoclonal Antibody (K01_2M22)
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Fibulin 3 Antibody (MA564052) in IHC (P)
Immunohistochemistry (Paraffin) analysis of Fibulin 3 in paraffin-embedded Human breast cancer tissue. Samples were incubated with Fibulin 3 recombinant monoclonal (Product # MA564052). High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.
产品信息
MA564052
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
Expression System
HEK293F
分类
Recombinant Monoclonal
类型
Antibody
克隆号
K01_2M22
抗原
Recombinant protein of human EFEMP1/Fibulin-3 (aa 18-493).
偶联物
形式
Liquid
浓度
0.60 mg/mL
纯化类型
Protein A/G
保存液
50mM tris glycine, pH 7.4, with 40% glycerol, 0.05% BSA, 150mM NaCl
内含物
0.01% sodium azide
保存条件
Maintain refrigerated at 2-8°C for up to 1 month. For long term storage store at -20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: QDTEETITYT QCTDGYEWDP VRQQCKDIDE CDIVPDACKG GMKCVNHYGG YLCLPKTAQI IVNNEQPQQE TQPAEGTSGA TTGVVAASSM ATSGVLPGGG FVASAAAVAG PEMQTGRNNF VIRRNPADPQ RIPSNPSHRI QCAAGYEQSE HNVCQDIDEC TAGTHNCRAD QVCINLRGSF ACQCPPGYQK RGEQCVDIDE CTIPPYCHQR CVNTPGSFYC QCSPGFQLAA NNYTCVDINE CDASNQCAQQ CYNILGSFIC QCNQGYELSS DRLNCEDIDE CRTSSYLCQY QCVNEPGKFS CMCPQGYQVV RSRTCQDINE CETTNECRED EMCWNYHGGF RCYPRNPCQD PYILTPENRC VCPVSNAMCR ELPQSIVYKY MSIRSDRSVP SDIFQIQATT IYANTINTFR IKSGNENGEF YLRQTSPVSA MLVLVKSLSG PREHIVDLEM LTVSSIGTFR TSSVLRLTII VGPFSF
Highest antigen sequence identity to the following orthologs: Mouse - 95%, Rat - 93%, Pig - 95%, Cynomolgus monkey - 99%.
靶标信息
This gene encodes a member of the fibulin family of extracellular matrix glycoproteins. Like all members of this family, the encoded protein contains tandemly repeated epidermal growth factor-like repeats followed by a C-terminus fibulin-type domain. This gene is upregulated in malignant gliomas and may play a role in the aggressive nature of these tumors. Mutations in this gene are associated with Doyne honeycomb retinal dystrophy. Alternatively spliced transcript variants that encode the same protein have been described.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: EGF containing fibulin-like extracellular matrix protein 1; EGF-containing fibulin-like extracellular matrix protein 1; Extracellular protein S1-5; FIBL-3; Fibrillin-like protein; Fibulin-3; FLJ35535; MGC111353
基因别名: DHRD; DRAD; EFEMP1; FBLN3; FBNL; FIBL-3; MLVT; MTLV; S1-5
UniProt ID: (Human) Q12805
Entrez Gene ID: (Human) 2202
regulation of transcription, DNA-templated
epidermal growth factor receptor signaling pathway
visual perception
positive regulation of cell proliferation
negative regulation of neuron projection development
peptidyl-tyrosine phosphorylation
positive regulation of cell projection organization
negative regulation of chondrocyte differentiation
camera-type eye development
embryonic eye morphogenesis
post-embryonic eye morphogenesis
regulation of glial cell migration
