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Invitrogen
Fibulin 5 Polyclonal Antibody
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产品信息
PA5-18568
产品规格
种属反应
Human
宿主/亚型
Goat
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide sequence (RPIKGPREIQLDLE) corresponding to the internal amino acids of FBLN5 (aa 408-422).
偶联物
形式
Liquid
浓度
0.5 mg/mL
规格
100 µg
纯化类型
Ammonium sulfate precipitation
保存液
TBS, pH 7.3, with 0.5% BSA
内含物
0.02% sodium azide
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
This antibody is predicted to react with canine, mouse and rat based on sequence homology.
This antibody is tested in Peptide ELISA: antibody detection limit dilution 32,000.
靶标信息
Essential for elastic fiber formation, is involved in the assembly of continuous elastin (ELN) polymer and promotes the interaction of microfibrils and ELN. Stabilizes and organizes elastic fibers in the skin, lung and vasculature. Promotes adhesion of endothelial cells through interaction of integrins and the RGD motif. Vascular ligand for integrin receptors which may play a role in vascular development and remodeling.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: 50kD; similar to human S1-5 encoded by GenBank Accession Number U03877; DANCE; Developmental arteries and neural crest EGF-like protein; embryonic vascular EGF-like repeat-containing protein; FBLN5; FIBL-5; Fibulin-5; FLJ90059; testis tissue sperm-binding protein Li 75n; unnamed protein product; UP50; Urine p50 protein
基因别名: ADCL2; ARCL1A; ARMD3; CMT1H; DANCE; EVEC; FBLN5; FIBL-5; HNARMD; UNQ184/PRO210; UP50
UniProt ID: (Human) Q9UBX5
Entrez Gene ID: (Human) 10516
negative regulation of transcription from RNA polymerase II promoter
cell adhesion
cell-matrix adhesion
negative regulation of angiogenesis
extracellular matrix organization
positive regulation of osteoblast proliferation
protein localization to cell surface
positive regulation of transcription from RNA polymerase II promoter
secretion
elastic fiber assembly
intramembranous bone growth
regulation of removal of superoxide radicals
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