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In direct ELISAs and Western blots, no cross-reactivity with recombinant human Ficolin-2 is observed.
Reconstitute at 0.5 mg/mL in sterile PBS.
H-Ficolin (Hakata antigen, Ficolin-3) is an innate immunity pattern recognition molecule found in human serum. H-Ficolin binds to distinct pathogen-associated molecular patterns (PAMP) formed by carbohydrates (GlcNAc, GalNAc and fucose) activating complement through the lectin pathway by means of the associated MASPs ((MBL)-associated serine proteases). H-Ficolin consists of 35 kDa protein chains associated in triplet subunits which are again associated in high molecular weight oligomers by means of disulfide bonds at the N-terminal region.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Collagen/fibrinogen domain-containing lectin 3 p35; Collagen/fibrinogen domain-containing protein 3; Ficolin-3; Hakata antigen; MGC22543
基因别名: FCN3; FCNH; HAKA1
UniProt ID: (Human) O75636
Entrez Gene ID: (Human) 8547