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NeoBiotechnologies
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Product cellular localization: Cytoplasmic granule.
Positive control: Human skin.
Tissue specificity: Expressed in skin, thymus, stomach, tonsils, testis, placenta, kidney, pancreas, mammary gland, bladder, thyroid, salivary gland and trachea, but not detected in heart, brain, liver, lung, bone marrow, small intestine, spleen, prostate, colon, or adrenal gland (PubMed:19384417). In the skin, mainly expressed in stratum granulosum of the epidermis (PubMed:1429717) (PubMed:19384417).
Filaggrin is expressed only in well differentiated keratinized epithelial cells. The synthesis of filaggrin varies in types of ichthyosis, and with viral, premalignant and malignant conditions.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: epidermal filaggrin; Filaggrin
基因别名: ATOD2; FLG
UniProt ID: (Human) P20930
Entrez Gene ID: (Human) 2312