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Invitrogen
Filamin B Monoclonal Antibody (11E2D2)
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Filamin B Antibody (MA5-49226) in ICC/IF
Immunocytochemistry analysis of Filamin B in Hela cells. Enzyme antigen retrieval was performed using IHC enzyme antigen retrieval reagent for 15 mins. The cells were blocked with 10% goat serum. Samples were then incubated in Filamin B Monoclonal antibody (Product # MA5-49226) using a dilution of 5 μg/mL. DyLight®488 Conjugated Goat Anti-Mouse IgG was used as secondary antibody at 1:100 dilution and incuba... View More
产品信息
MA5-49226
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG1
分类
Monoclonal
类型
Antibody
克隆号
11E2D2
抗原
E.coli-derived human Filamin B/FLNB recombinant protein (Position: Q397-D701).
偶联物
形式
Lyophilized
浓度
500 µg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS with 4mg trehalose
内含物
no preservative
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Adding 0.2 mL of distilled water will yield a concentration of 500 µg/mL.
Positive Control - WB: human A549 whole cell. IHC: human lung cancer tissue, human lymph node of rectal cancer tissue, human metaplasia of squamous cells of the renal pelvis tissue, human spleen tissue. ICC/IF: Hela cell.|Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
靶标信息
FOXK1 is expressed in these cells and regulates cell cycle progression through an interaction with its downstream target the cyclin-dependent kinase inhibitor p21 (CIP). Loss of FOXK1 in mice results in growth retardation and a severe impairment in skeletal muscle regeneration following injury. FOXK1 also shows expression in immature tissues of brain, eye, heart, lung and thymus. It also is predominantly expressed in many malignant tissues, such as tumors of the brain, colon and lymph node.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: ABP-278; ABP-280 homolog; actin binding protein 278; Actin-binding-like protein; Beta-filamin; Fh1; filamin B, beta; Filamin homolog 1; Filamin-3; Filamin-B; FilaminB; FLN-B; Larsen syndrome 1 (autosomal dominant); Thyroid autoantigen; Truncated ABP; Truncated actin-binding protein
基因别名: ABP-278; ABP-280; AOI; FH1; FLN-B; FLN1L; FLN3; FLNB; LRS1; SCT; TABP; TAP
UniProt ID: (Human) O75369
Entrez Gene ID: (Human) 2317
