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Invitrogen
Fluoxetine Recombinant Mouse Monoclonal Antibody (3A8)
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Fluoxetine Antibody (MA566488) in SDS-PAGE
SDS-PAGE characterization of Fluoxetine under reducing conditions. Lane M: Protein marker (kDa); Lane FXT: Purified Fluoxetine Recombinant Monoclonal (Product # MA566488). Fluoxetine showing heavy chain (~50 kDa) and light chain (~25 kDa). Gels were stained with Coomassie Brilliant Blue R-666.
产品信息
MA566488
产品规格
种属反应
Chemical
宿主/亚型
Mouse
/ IgG
Expression System
CHO cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
3A8
抗原
Conjugate of FXT hapten and KLH.
偶联物
形式
Liquid
浓度
12.3 mg/mL
纯化类型
Protein G
保存液
PBS
内含物
0.09% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
靶标信息
Fluoxetine, commonly known as Prozac, is a selective serotonin reuptake inhibitor (SSRI) developed by Eli Lilly and Company. It is primarily used to treat major depressive disorder, obsessive-compulsive disorder, and other psychological conditions. Fluoxetine functions by inhibiting the serotonin transporter (SERT), thereby increasing serotonin levels in the brain. The gene regulatory changes associated with fluoxetine have been characterized through multi-omics analyses, revealing its impact on various brain regions. The drug's pharmacogenetics indicate that genetic variations can influence its efficacy and response in patients. Fluoxetine also promotes adult neurogenesis, particularly in the hippocampus, which is mediated by the 5-HT3 receptor. This structural plasticity is crucial for its therapeutic effects in treating depression and other CNS disorders.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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