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NeoBiotechnologies
Fodrin/Alpha Spectrin II (SPTAN1)/NEAS Monoclonal Antibody (SPTAN1/3507)
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产品信息
6709-MSM7-P1
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG
分类
Monoclonal
类型
Antibody
克隆号
SPTAN1/3507
抗原
Recombinant fragment of human SPTAN1 protein (around aa 2351-2475).
偶联物
形式
Liquid
浓度
200 µg/mL
纯化类型
Protein A/G
保存液
PBS with 0.05% BSA
内含物
0.05% sodium azide
保存条件
4°C
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Antibody is stable for 24 months.
Positive Control: Human colon or kidney tissues (IHC). Cellular Localization: Cytoplasm
Specificity Comments: Spectrin, an actin binding protein that is a major component of the cytoskeletal superstructure of the erythrocyte plasma membrane, is essential in determining the properties of the membrane including its shape and deformability. Spectrins function as membrane organizers and stabilizers, composed of nonhomologous II, a neuronal cytoskeleton protein.
靶标信息
SPTAN1 (spectrin alpha chain, non-erythrocytic 1) is a part of the spectrin family of filamentous cytoskeletal proteins. They function as essential scaffold proteins that stabilize the plasma membrane and organize intracellular organelles. Spectrins are composed of alpha and beta dimers that associate to form tetramers linked in a head-to-head arrangement. SPTAN1 has been implicated in other cellular functions including DNA repair and cell cycle regulation. Mutations in this gene are the cause of early infantile epileptic encephalopathy-5. Alternate splicing results in multiple transcript variants.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: (ALPHA)II-SPECTRIN; alpha; alpha-fodrin; Alpha-II spectrin; brain; FLJ44613; Fodrin alpha chain; Non erythrocytic spectrin alpha; non-erythrocytic 1 (alpha-fodrin); non-erythroid alpha chain; Spectrin; Spectrin alpha; Spectrin alpha chain brain; Spectrin alpha chain, non-erythrocytic 1; spectrin, non-erythroid alpha chain; Spectrin, non-erythroid alpha subunit
基因别名: EIEE5; NEAS; SPTA2; SPTAN1
UniProt ID: (Human) Q13813
Entrez Gene ID: (Human) 6709
