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Invitrogen
Folate Receptor alpha Recombinant Human Monoclonal Antibody (4B11)
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Folate Receptor alpha Antibody (MA5-60740) in ELISA
ELISA analysis of Folate Receptor alpha. Samples were incubated with Folate Receptor alpha Recombinant Monoclonal antibody (Product # MA5-60740) using a dilution of 2 µg/mL. Activity: Measured by its binding ability in a functional ELISA. The EC50 is 6.893-7.883 ng/mL.
产品信息
MA5-60740
产品规格
种属反应
Cynomolgus monkey,
Human
宿主/亚型
Human
/ IgG1
Expression System
HEK293F
分类
Recombinant Monoclonal
类型
Antibody
克隆号
4B11
抗原
Recombinant Human FOLR1 protein.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.03% ProClin 300
保存条件
-20°C or -80°C if preferred
运输条件
Ambient (domestic); Wet ice (international)
RRID
靶标信息
The protein encoded by this gene is a member of the folate receptor family. Members of this gene family bind folic acid and its reduced derivatives, and transport 5-methyltetrahydrofolate into cells. This gene product is a secreted protein that either anchors to membranes via a glycosyl-phosphatidylinositol linkage or exists in a soluble form. Mutations in this gene have been associated with neurodegeneration due to cerebral folate transport deficiency. Due to the presence of two promoters, multiple transcription start sites, and alternative splicing, multiple transcript variants encoding the same protein have been found for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Adult folate-binding protein; FBP; folate binding protein; Folate receptor 1; folate receptor 1 (adult); Folate receptor alpha; Folate receptor, adult; FR-alpha; KB cells FBP; MOv18; Ovarian tumor-associated antigen MOv18
基因别名: FBP; FOLR; FOLR1
UniProt ID: (Human) P15328
Entrez Gene ID: (Human) 2348, (Cynomolgus monkey) 102132305
heart looping
neural crest cell migration involved in heart formation
cardiac neural crest cell migration involved in outflow tract morphogenesis
ER to Golgi vesicle-mediated transport
receptor-mediated endocytosis
folic acid transport
regulation of transforming growth factor beta receptor signaling pathway
axon regeneration
folic acid metabolic process
COPII vesicle coating
regulation of canonical Wnt signaling pathway
pharyngeal arch artery morphogenesis
anterior neural tube closure
cellular response to folic acid
