Search
Invitrogen
Folliculin Polyclonal Antibody
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
Additional Information:
{{banner.description}}
图: 1 / 3
Folliculin Antibody (PA5-100247) in ICC/IF
Immunofluorescent analysis of Folliculin in HeLa cells. Samples were fixed with paraformaldehyde, permeabilized with 0.1% Triton X-100, blocked with 10% serum (45 min at 25°C), incubated with mouse anti-beta tubulin and Folliculin polyclonal antibody (Product # PA5-100247) using a dilution of 1:200 (1 hr, 37°C), and followed by goat anti-rabbit IgG Alexa Fluor 594 (red) and goat anti-mouse IgG Alexa Fluor 4... View More
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-100247
产品规格
种属反应
Human,
Mouse,
Non-human primate,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human FLCN(Accession Q8NFG4), corresponding to amino acid residues S56-Y106.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Antibody detects endogenous levels of total FLCN.
靶标信息
This gene encodes a mitochondrial protein that is characterized by a poly-proline rich region. A chicken homolog of this protein promotes mitochondrial fission and the mouse homolog protects cells from oxidative stress. A related pseudogene of this gene is found on chromosome X.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
篇参考文献 (0)
您是否在文献中引用过该产品？请点击下方按钮邮件告知我们。
生物信息学
蛋白别名: BHD skin lesion fibrofolliculoma protein; Birt-Hogg-Dube syndrome protein; Birt-Hogg-Dube syndrome protein homolog; Folliculin; unnamed protein product
基因别名: AU014660; B430214A04Rik; BHD; DENND8B; FLCL; FLCN
UniProt ID: (Human) Q8NFG4, (Mouse) Q8QZS3, (Rat) Q76JQ2
Entrez Gene ID: (Human) 201163, (Mouse) 216805, (Rat) 303185
negative regulation of transcription from RNA polymerase II promoter
in utero embryonic development
lysosome organization
cell-cell junction assembly
transforming growth factor beta receptor signaling pathway
negative regulation of cell proliferation
cellular response to starvation
positive regulation of autophagy
hemopoiesis
positive regulation of transforming growth factor beta receptor signaling pathway
SCF-dependent proteasomal ubiquitin-dependent protein catabolic process
protein destabilization
cellular response to nutrient levels
TOR signaling
regulation of TOR signaling
negative regulation of TOR signaling
positive regulation of TOR signaling
lysosome localization
cellular response to amino acid starvation
negative regulation of Rho protein signal transduction
intracellular signal transduction
TORC1 signaling
positive regulation of apoptotic process
protein kinase B signaling
negative regulation of glycolytic process
negative regulation of transcription, DNA-templated
regulation of Ras protein signal transduction
epithelial cell proliferation
negative regulation of epithelial cell proliferation
negative regulation of protein kinase B signaling
ERK1 and ERK2 cascade
negative regulation of ERK1 and ERK2 cascade
cell proliferation involved in kidney development
energy homeostasis
intrinsic apoptotic signaling pathway
negative regulation of cold-induced thermogenesis
negative regulation of protein localization to nucleus
negative regulation of cell proliferation involved in kidney development
negative regulation of post-translational protein modification
negative regulation of intracellular signal transduction
negative regulation of brown fat cell differentiation
positive regulation of TORC1 signaling
negative regulation of lysosome organization
regulation of pro-B cell differentiation
positive regulation of intrinsic apoptotic signaling pathway
regulation of protein phosphorylation
positive regulation of protein phosphorylation
negative regulation of gene expression
negative regulation of mitochondrion organization
negative regulation of angiogenesis
negative regulation of cell growth
negative regulation of cell migration
regulation of cytokinesis
regulation of histone acetylation
positive regulation of cell adhesion
positive regulation of transcription from RNA polymerase II promoter
negative regulation of cellular respiration
negative regulation of mitochondrial DNA metabolic process
negative regulation of muscle tissue development
negative regulation of energy homeostasis
negative regulation of ATP biosynthetic process
biological_process
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
