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Invitrogen
Fra2 Polyclonal Antibody
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Fra2 Antibody (PA5-95286) in WB
Western blot analysis of Fra2 in Lane 1: rat lung tissue lysate (50 µg), Lane 2: HEPG2 whole cell lysate (40 µg), Lane 3: A549 whole cell lysate (40 µg), Lane 4: SW620 whole cell lysate (40 µg). Samples were incubated with Fra2 polyclonal antibody (Product # PA5-95286).
产品信息
PA5-95286
产品规格
种属反应
Human,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthetic peptide corresponding to a sequence at the N-terminus of human FRA2 (96-127aa ALPRPGVIKTIGTTVGRRRRDEQLSPEEEEKR).
偶联物
形式
Lyophilized
浓度
500 µg/mL
纯化类型
Affinity chromatography
保存液
PBS with 4mg trehalose
内含物
0.05mg sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.
Positive Control - WB: Rat Lung Tissue, HEPG2 whole cell, A549 whole cell, SW620 whole cell.|Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
靶标信息
The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: FOS like 2, AP-1 trancription factor subunit; FOS like antigen 2; FOS-like antigen 2; Fos-related antigen 2; FRA-2
基因别名: FOSL2; Fra-2; FRA2
UniProt ID: (Human) P15408, (Rat) P51145
Entrez Gene ID: (Human) 2355, (Rat) 25446
RNA polymerase II core promoter proximal region sequence-specific DNA binding
transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding
chromatin binding
transcription factor activity, sequence-specific DNA binding
protein binding
RNA polymerase II regulatory region sequence-specific DNA binding
DNA binding
double-stranded DNA binding
sequence-specific DNA binding
transcription regulatory region DNA binding
protein heterodimerization activity
basic leucine zipper transcription factor
keratinocyte development
transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
cell death
positive regulation of transcription from RNA polymerase II promoter
positive regulation of fibroblast proliferation
conditioned taste aversion
response to hypoxia
transcription from RNA polymerase II promoter
female pregnancy
aging
circadian rhythm
response to cold
response to light stimulus
response to mechanical stimulus
response to toxic substance
photoperiodism
response to organic cyclic compound
sleep
response to estradiol
response to progesterone
response to cytokine
response to immobilization stress
response to peptide hormone
positive regulation of transcription, DNA-templated
response to cAMP
