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Rockland
Frequenin Polyclonal Antibody
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Frequenin Antibody (600-401-216) in ICC/IF
Hippocampal neurons were prepared from 17 d old NMRI mice and grown as described previously (G. Grosse et al., (2000) J. Neurosci. 20: 1869-1882). The figure shows the distribution of neuronal calcium sensor-1 (NCS-1) (red) and synaptobrevin (green) in hippocampal cell cultures after 19 d in vitro. Numerous synapses immunoreactive for synaptobrevin also show NCS-1 immunoreactivity. NCS-1 derived from invert... View More
产品信息
600-401-216
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Frequenin (recombinant from Mouse with extensive post-translational modifications)
偶联物
形式
Liquid
浓度
2 mg/mL
纯化类型
Affinity chromatography
保存液
0.02M potassium phosphate, pH 7.2, with 0.15M NaCl
内含物
0.01% sodium azide
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
Assay by immunoelectrophoresis resulted in a single precipitin arc against anti-Rabbit Serum.
靶标信息
This gene is a member of the neuronal calcium sensor gene family, which encode calcium-binding proteins expressed predominantly in neurons. The protein encoded by this gene regulates G protein-coupled receptor phosphorylation in a calcium-dependent manner and can substitute for calmodulin. The protein is associated with secretory granules and modulates synaptic transmission and synaptic plasticity. Multiple transcript variants encoding different isoforms have been found for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: frequenin; Frequenin homolog; Frequenin-like protein; Frequenin-like ubiquitous protein; NCS-1; Neuronal calcium sensor 1; neuronal calcium sensor-1
基因别名: 9430075O15Rik; A730032G13Rik; AI836659; FLUP; FREQ; Mfreq; NCS-1; NCS1
UniProt ID: (Human) P62166, (Mouse) Q8BNY6, (Rat) P62168
Entrez Gene ID: (Human) 23413, (Mouse) 14299, (Rat) 65153
