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This intronless gene is a member of the frizzled gene family. Members of this family encode seven-transmembrane domain proteins that are receptors for the wingless type MMTV integration site family of signaling proteins. This gene encodes a protein that is coupled to the beta-catenin canonical signaling pathway. Competition between the wingless-type MMTV integration site family, member 3A and wingless-type MMTV integration site family, member 5A gene products for binding of this protein is thought to regulate the beta-catenin-dependent and -independent pathways.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Dfrizzled2; Drosophila polarity gene (frizzled) homologue; Drosophila polarity gene homolog 2; frizzled 2; frizzled 2, seven transmembrane spanning receptor; frizzled class receptor 2; frizzled family receptor 2; frizzled homolog 2; Frizzled-10; Frizzled-2; Fz-10; Fz-2; FzE2; mFz2; rFz2
基因别名: AL033370; AW456835; Frizzled-2; Fz-10; fz-2; Fz10; Fz2; Fzd10; FZD2; fzE2; hFz2; I79_011598; Mfz10; Mfz10a
UniProt ID: (Human) Q14332, (Rat) Q08464, (Mouse) Q9JIP6