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In direct ELISAs, approximately 30% cross-reactivity with recombinant mouse (rm) Frizzled-1 is observed and less than 5% cross-reactivity with rmFrizzled-4, recombinant human Frizzled-5, rmFrizzled-6, and rmFrizzled-8 is observed.
Reconstitute at 0.2 mg/mL in sterile PBS.
Endoxin level is <0.50 EU per 1 µg of the antibody by the LAL method.
This intronless gene is a member of the frizzled gene family. Members of this family encode seven-transmembrane domain proteins that are receptors for the wingless type MMTV integration site family of signaling proteins. This gene encodes a protein that is coupled to the beta-catenin canonical signaling pathway. Competition between the wingless-type MMTV integration site family, member 3A and wingless-type MMTV integration site family, member 5A gene products for binding of this protein is thought to regulate the beta-catenin-dependent and -independent pathways.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Dfrizzled2; Frizzled-10; Frizzled-2; Fz-10; Fz-2; mFz2
基因别名: AL033370; AW456835; Fz10; Fzd10; Fzd2; Mfz10; Mfz10a
UniProt ID: (Mouse) Q9JIP6
Entrez Gene ID: (Mouse) 57265