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Invitrogen
FucGM1 (Atigotatug Biosimilar) Recombinant Human Monoclonal Antibody
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产品信息
MA562588
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
宿主/亚型
Human
/ IgG1, kappa
Expression System
CHO cells
分类
Recombinant Monoclonal
类型
Antibody
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1.4 mg/mL
规格
100 µg
纯化类型
Protein A/G
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
靶标信息
FucGM1 is a fucosylated ganglioside and a tumor-associated glycolipid antigen expressed on the surface of certain cancer cells, most notably small cell lung cancer (SCLC). It is a modified form of the GM1 ganglioside in which a fucose residue is added to the carbohydrate moiety. FucGM1 is minimally expressed in most normal adult tissues but is highly upregulated in specific malignancies, making it a promising target for antibody-based therapies and cancer vaccines. Due to its cell surface localization and tumor-restricted expression pattern, FucGM1 is widely studied as a biomarker and immunotherapeutic target in oncology.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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