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Invitrogen
Furosemide Recombinant Mouse Monoclonal Antibody (1B1)
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Furosemide Antibody (MA566476) in SDS-PAGE
SDS-PAGE characterization of Furosemide under reducing conditions. Lane M: Protein marker (kDa); Lane FSM: Purified Furosemide Recombinant Monoclonal (Product # MA566476). Furosemide showing heavy chain (~50 kDa) and light chain (~25 kDa). Gels were stained with Coomassie Brilliant Blue R-650.
产品信息
MA566476
产品规格
种属反应
Chemical
宿主/亚型
Mouse
/ IgG
Expression System
CHO cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
1B1
抗原
Conjugate of FSM hapten and KLH.
偶联物
形式
Liquid
浓度
3.4 mg/mL
纯化类型
Protein G
保存液
PBS
内含物
0.09% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
靶标信息
Furosemide, a loop diuretic, is commonly used to treat edema associated with congestive heart failure, liver cirrhosis, and renal disease. It functions by inhibiting the reabsorption of sodium and chloride in the kidneys, specifically at the ascending loop of Henle, leading to increased urine output. Furosemide is available in various formulations, including brand-name and generic versions, which have been shown to be bioequivalent in clinical studies. The pharmacokinetic and pharmacodynamic profiles of these formulations are similar, ensuring consistent therapeutic effects across different brands. Furosemide's effectiveness is measured by its ability to increase urine output and sodium excretion, which are critical parameters in managing fluid overload conditions. Despite its benefits, furosemide can cause electrolyte imbalances, necessitating careful monitoring during treatment.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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