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Alomone Labs, LTD
GABA(B) R2 Polyclonal Antibody
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GABA(B) R2 Antibody (AGB-002-200UL) in IHC (F)
Expression of GABA (B) receptor 2 in mouse hippocampus - Immunohistochemical staining of mouse hippocampus frozen sections using Anti-GABA (B) R2 Antibody (#AGB-002 ), (1:100). A. GABBR2 staining (green)is detected in layers including the stratum lacunosum molecular (SLM) and stratum radiatum of the CA3 layer (star). B. Staining with mouse Anti-GAP43 Antibody (red)sets apart the SLM. C. Confocal merge sugge... View More
产品信息
AGB-002-200UL
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
CKDPIEDINSPEHIQRRLSL, corresponding to amino acid residues 875-894 of human GABBR2, Intracellular, C-terminus
偶联物
形式
Lyophilized
浓度
0.85 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.4, with 1% BSA
内含物
0.05% sodium azide
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Reconstitution: 50 µL or 0.2 mL double distilled water (DDW), depending on the sample size. The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20C. The reconstituted solution can be stored at 4C, protected from the light, for up to 1 week. For longer periods, small aliquots should be stored at -20C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 X g 5 min).
靶标信息
The multi-pass membrane protein, GABBR2, belongs to the G-protein coupled receptor 3 family and GABA-B receptor subfamily. The GABA-B receptors inhibit neuronal activity through G protein-coupled second-messenger systems, which regulate the release of neurotransmitters, and the activity of ion channels and adenylyl cyclase. This receptor subunit forms an active heterodimeric complex with GABA-B receptor subunit 1, neither of which is effective on its own. Allelic variants of this gene have been associated with nicotine dependence.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: FLJ36928; G protein-coupled receptor 51; G-protein coupled receptor 51; GABA BR; GABA-B R2 receptor; GABA-B receptor 2; GABA-B receptor, R2 subunit; GABA-B-R2; GABA-BR2; GABABR2; gamma-aminobutyric acid; gamma-aminobutyric acid (GABA) B receptor, 2; gamma-aminobutyric acid B receptor 2; Gamma-aminobutyric acid type B receptor subunit 2; gamma-aminobutyric acid type B receptor, subunit 2; gb2; HG20; MGC119386; MGC119388; MGC119389; ortholog of human G protein-coupled receptor 51 GPR51; RP23-337N2.1
基因别名: GABABR2; GABBR2; Gb2; Gm425; GPR51; GPRC3B; HG20; HRIHFB2099
UniProt ID: (Human) O75899, (Rat) O88871, (Mouse) Q80T41
Entrez Gene ID: (Human) 9568, (Rat) 83633, (Mouse) 242425
