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Invitrogen
GALC Recombinant Rabbit Monoclonal Antibody (PSH04-32)
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GALC Antibody (MA557850) in IHC (P)
Immunohistochemical analysis of GalC was performed using formalin-fixed paraffin-embedded human brain frontal cortex tissue sections. To expose the target protein, heat-induced epitope retrieval was performed on de-paraffinized sections using eBioscience™ IHC Antigen Retrieval Solution - High pH (10X) (Product # 00-4956-58) diluted to 1X solution in water in a decloaking chamber at 110 degree Celsius for 15... View More
产品信息
MA557850
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
Expression System
HEK293 cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
PSH04-32
抗原
Recombinant protein within human GALC aa 1-500 / 685.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein A
保存液
PBS, pH 7.4, with 0.1% BSA, 40% glycerol
内含物
0.05% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Positive Control: 293T cell lysate, A375 cell lysate, A549 cell lysate, SH-SY5Y cell lysate, HaCaT cell lysate, human brain tissue, human liver cancer tissue.
Tissue Specificity: Low tissue specificity.
Subcellular Location: Lysosome.
Sequence Similarities: 85% Mouse.
Predicted band size: 77 kDa.
靶标信息
This gene encodes a lysosomal protein which hydrolyzes the galactose ester bonds of galactosylceramide, galactosylsphingosine, lactosylceramide, and monogalactosyldiglyceride. Mutations in this gene have been associated with Krabbe disease, also known as globoid cell leukodystrophy. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: 3.2.1.46; beta-galactosidase; Galactocerebrosidase; Galactocerebroside beta-galactosidase; Galactosylceramidase; Galactosylceramide beta-galactosidase; galactosylceraminidase; GALCERase; testis tissue sperm-binding protein Li 88E; testis tissue sperm-binding protein Li 89A
基因别名: GALC
UniProt ID: (Human) B7Z7Z2
Entrez Gene ID: (Human) 2581
