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Invitrogen
GALR3 Polyclonal Antibody
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产品信息
PA5-28747
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide encompassing a sequence within the Extracellular domain of human GALR3. The exact sequence is proprietary.
偶联物
形式
Liquid
浓度
0.72 mg/mL
纯化类型
Antigen affinity chromatography
保存液
0.1M tris glycine, pH 7, with 10% glycerol
内含物
0.01% thimerosal
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Recommended positive controls: A431, H1299, HeLa, HepG2, Molt-4, Raji, mouse eye, mouse brain, rat brain.
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
靶标信息
The neuropeptide galanin modulates a variety of physiologic processes including cognition/memory, sensory/pain processing, hormone secretion, and feeding behavior. The human galanin receptors are G protein-coupled receptors that functionally couple to their intracellular effector through distinct signaling pathways. GALR3 is found in many tissues and may be expressed as 1.4-, 2.4-, and 5-kb transcripts. GALR3 has been reported in brain, testis, adrenal gland, and pancreas. An EST has been isolated from an ovarian thecoma fibroma library.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Gal receptor-3; Gal-r3; Gal3 receptor; GAL3-R; Galanin r3 receptor; Galanin receptor type 3; galanin receptor, family member 3; GALR-3; OTTHUMP00000028820
基因别名: GALNR3; GALR3
UniProt ID: (Human) O60755, (Mouse) O88853, (Rat) O88626
Entrez Gene ID: (Human) 8484, (Mouse) 14429, (Rat) 29235
adenylate cyclase-modulating G-protein coupled receptor signaling pathway
negative regulation of adenylate cyclase activity
phospholipase C-activating G-protein coupled receptor signaling pathway
neuropeptide signaling pathway
chemical synaptic transmission
learning or memory
feeding behavior
positive regulation of transcription from RNA polymerase II promoter
adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway
negative regulation of cAMP biosynthetic process
