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Alomone Labs, LTD
GALR3 (extracellular) Polyclonal Antibody
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GALR3 (extracellular) Antibody (AGR-013-200UL) in IHC
Expression of Galanin receptor 3 in rat hippocampus - Immunohistochemical staining of rat hippocampus using Anti-GALR3 (extracellular) Antibody (#AGR-013). A. Galanin receptor 3 (green) appears in apical dendrites of pyramidal neurons in CA1 (arrows). B. MAP2 (red), a marker of axons and dendrites, is stained in the same section. GALR3 appears to be expressed in a subset of apical dendrites (arrows). DAPI i... View More
产品信息
AGR-013-200UL
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
SYYGTVRYGALELC, corresponding to amino acid residues 159-172 of mouse Galanin receptor type 3, 2nd extracellular loop
偶联物
形式
Lyophilized
浓度
0.7 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.4, with 1% BSA
内含物
0.05% sodium azide
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Reconstitution: 25 µL, 50 µL or 0.2 mL double distilled water (DDW), depending on the sample size. The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20C. The reconstituted solution can be stored at 4C for up to 1 week. For longer periods, small aliquots should be stored at -20C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).
靶标信息
The neuropeptide galanin modulates a variety of physiologic processes including cognition/memory, sensory/pain processing, hormone secretion, and feeding behavior. The human galanin receptors are G protein-coupled receptors that functionally couple to their intracellular effector through distinct signaling pathways. GALR3 is found in many tissues and may be expressed as 1.4-, 2.4-, and 5-kb transcripts. GALR3 has been reported in brain, testis, adrenal gland, and pancreas. An EST has been isolated from an ovarian thecoma fibroma library.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Gal receptor-3; Gal-r3; Gal3 receptor; GAL3-R; Galanin r3 receptor; Galanin receptor type 3; galanin receptor, family member 3; GALR-3; OTTHUMP00000028820
基因别名: GALNR3; GALR3
UniProt ID: (Human) O60755, (Mouse) O88853, (Rat) O88626
Entrez Gene ID: (Human) 8484, (Mouse) 14429, (Rat) 29235
adenylate cyclase-modulating G-protein coupled receptor signaling pathway
negative regulation of adenylate cyclase activity
phospholipase C-activating G-protein coupled receptor signaling pathway
neuropeptide signaling pathway
chemical synaptic transmission
learning or memory
feeding behavior
positive regulation of transcription from RNA polymerase II promoter
adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway
negative regulation of cAMP biosynthetic process
