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Invitrogen
GAP43 Polyclonal Antibody
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图: 1 / 7
GAP43 Antibody (PA1-16729) in ICC/IF
Immunocytochemistry analysis of GAP43 in Cortical neuron-glial cell culture from E20 rat. Samples were incubated in GAP43 polyclonal antibody (Product # PA1-16729) using a dilution of 1:2000. This antibody in green, and costained with mouse mAb to vimentin, dilution 1:2,000, in red. Blue: DAPI staining of nuclear DNA. GAP43 antibody labels protein expressed in the axonal membrane of neuronal cells, while vimentin antibody stains intermediate filaments in fibroblasts and other non-neuronal cells.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA1-16729
应用
建议稀释比
已发表文章
产品规格
种属反应
Bovine,
Dog,
Chicken,
Fruit fly,
Horse,
Human,
Mouse,
Non-human primate,
Pig,
Rat
已发表种属
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
C-terminal peptide of rodent GAP43 coupled to KLH.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
Antigen affinity chromatography
保存液
PBS with 50% glycerol
内含物
0.035% sodium azide
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Suggested positive control: embryonic nervous tissue, brain, injured nerve.
Immunogen sequence: KEDPEADQEH A
靶标信息
GAP43 (Neuromodulin) is associated with nerve growth. GAP43 is expressed by developing and regenerating neurons, and to a lesser extent reactive glial cells. It is a major component of the motile "growth cones" that form the tips of elongating axons. GAP43 also plays a role in axonal and dendritic filopodia induction.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: axonal membrane protein GAP-43; brain abundant, membrane attached signal protein 2; calmodulin-binding protein; calmodulin-binding protein P-57; GAP-43 protein; growth accentuating protein 43; growth-associated protein 43; MGC156666; nerve growth-related peptide GAP43; neural phosphoprotein B-50; neuron growth-associated protein 43; neuron protein F1; neuronal growth factor 43; protein F1; unnamed protein product
基因别名: B-50; Basp2; GAP-43; PP46
UniProt ID: (Chicken) P35001, (Human) P17677, (Bovine) P06836, (Mouse) P06837, (Rat) P07936
Entrez Gene ID: (Chicken) 427955, (Dog) 478572, (Horse) 100061125, (Human) 2596, (Pig) 100623423, (Bovine) 281777, (Mouse) 14432, (Rat) 29423
nervous system development
axon choice point recognition
axon regeneration
regulation of growth
tissue regeneration
axon guidance
glial cell differentiation
response to auditory stimulus
cell fate commitment
regulation of filopodium assembly
regulation of postsynaptic specialization assembly
phospholipase C-activating G-protein coupled receptor signaling pathway
response to wounding
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