Search
Agrisera
GAPC1/2/Glyceraldehyde-3-phosphate dehydrogenase (cytosolic) Polyclonal Antibody
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
Additional Information:
{{banner.description}}
图: 1 / 3
GAPC1/2/Glyceraldehyde-3-phosphate dehydrogenase (cytosolic) Antibody (AS15-2894) in WB
Samples: 1 – Synechocystis sp. PCC 6,803 wild type, 10 µg total protein extract 2 – Synechocystis cp 12 mutant, 10 µg total protein extract 3 – Synechocystis gap 1 mutant, 10 µg total protein extract 4 – Arabidopsis thaliana wildtype, 10 µg whole leaf extract 10 µg of total protein extracted freshly from Synechocystis sp. PCC 6,803 with 1 x PBS. Buffer components: 137 m M Na Cl, 10 m M Na 2 HPO 4*2 H 2 O, 2... View More
产品信息
AS15-2894
产品规格
种属反应
Bacteria,
Plant
宿主/亚型
Rabbit
分类
Polyclonal
类型
Antibody
抗原
KLH-conjugated synthetic peptide derived from Arabidopsis thaliana GAPC1 and GAPC2 proteins.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Lyophilized
规格
50 µg
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
4°C
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Store at 4°C; make aliquots to avoid working with a stock. Please remember to spin the tubes briefly prior to opening them to avoid any losses that might occur from material adhering to the cap or sides of the tube.
For reconstitution add 50 µL of sterile water.
Specific Species Reactivity: Arabidopsis thaliana, Synechocystis sp. PCC 6803
靶标信息
GAPC1 and GAPC2 encode highly similar cytosolic, NAD-dependent (phosphorylating) glyceraldehyde-3-phosphate dehydrogenases that predominantly localize to the cytoplasm but can relocalize to the nucleus under oxidative or metal stress. The proteins are ~338 amino acids and comprise the conserved N-terminal NAD(P)-binding domain and C-terminal catalytic domain typical of type I GAPDH enzymes, assembling as oligomeric dehydrogenases that drive central carbon metabolism. Catalytically, they convert glyceraldehyde-3-phosphate to 1,3-bisphosphoglycerate in glycolysis, with activity dependent on a key active-site cysteine (e.g., Cys149 in GAPC1) that is redox sensitive and can undergo reversible glutathionylation, linking enzyme function to cellular redox state. Beyond housekeeping glycolysis, genetic and cell-biological studies support broader roles in coordinating energy/redox homeostasis and development (including impacts on respiration, reactive oxygen species balance, and fertility/seed phenotypes when GAPC function is reduced) and in stress-responsive signaling, where hydrogen peroxide can promote nuclear accumulation of GAPC1/2 and association with transcriptional regulators to modulate gene expression programs involved in stem cell maintenance under oxidative stress.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
篇参考文献 (0)
您是否在文献中引用过该产品？请点击下方按钮邮件告知我们。
生物信息学
蛋白别名: GAPC; GAPC-1; GAPDH; T6J4.17; T6K12.26; T6K12_26
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
