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Invitrogen
GBP2 Polyclonal Antibody
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GBP2 Antibody (PA5-119701) in IHC (P)
Immunohistochemistry (Paraffin) analysis of paraffin-embedded human liver carcinoma tissue using GBP2 Polyclonal Antibody (Product # PA5-119701). The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0) for 20 minutes. The tissues were blocked in 5% BSA for 30 minutes at room temperature, washed with ddH2O and PBS, and then probed with the GBP2 antibody at a dilu... View More
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-119701
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide within human GBP2 aa 430-470.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
Affinity chromatography
保存液
TBS, pH 7.4, with 50% glycerol, 0.2% BSA
内含物
0.05% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Positive Control: SiHa cell lysate, human lung tissue lysate, human liver tissue, human liver carcinoma tissue, human colon tissue, human kidney tissue, A549.
Subcellular Location: Golgi apparatus membrane, Cytoplasm, perinuclear region, Membrane.
靶标信息
Binds GTP, GDP and GMP. Hydrolyzes GTP very efficiently; GDP rather than GMP is the major reaction product.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: GBP2; GTP-binding protein 2; guanine nucleotide-binding protein 2; guanylate binding protein 2, interferon-inducible; interferon-induced guanylate-binding protein 2; unnamed protein product
UniProt ID: (Human) P32456
Entrez Gene ID: (Human) 2634
activation of innate immune response
immune response
protein localization to nucleus
defense response to bacterium
defense response to protozoan
defense response to Gram-positive bacterium
defense response to virus
cytolysis in other organism
cellular response to lipopolysaccharide
cellular response to interferon-gamma
cellular response to interleukin-1
cellular response to tumor necrosis factor
positive regulation of pyroptotic inflammatory response
positive regulation of AIM2 inflammasome complex assembly
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Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
