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Invitrogen
GCN4 VHH-8His-Cys-tag Recombinant Alpaca Monoclonal Antibody (SAA1016)
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产品信息
MA5-54325
产品规格
种属反应
Yeast
宿主/亚型
Alpaca
/ VHH
Expression System
CHO cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
SAA1016
抗原
Recombinant Baker's yeast GCN4.
偶联物
形式
Liquid
浓度
0.25 mg/mL
纯化类型
Metal-chelate chromatography
保存液
PBS
内含物
no preservative
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
RRID
产品详细信息
Compatible with Direct ELISA
靶标信息
GCN4 is a transcription factor protein in yeast that plays a crucial role in the regulation of genes involved in amino acid biosynthesis, such as HIS4, HIS7, HIS3, ARG1, ARG3, ARG4, and ARG5,6. The protein contains a basic leucine zipper (bZIP) domain that enables it to bind to specific DNA sequences, thereby regulating the transcription of target genes. The protein is also involved in the regulation of other cellular processes, including stress response and nutrient signaling, such as GSH1, YAP1, and TRX2. Its structure is composed of a dimeric coiled-coil domain, which allows for protein-protein interactions, and a DNA-binding bZIP domain.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Amino acid biosynthesis regulatory protein; General control protein GCN4; General control transcription factor GCN4
基因别名: AAS101; AAS3; ARG9; GCN4; YEL009C
UniProt ID: (Baker's yeast) P03069
Entrez Gene ID: (Baker's yeast) 856709
RNA polymerase II core promoter proximal region sequence-specific DNA binding
RNA polymerase II transcription factor activity, sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding
DNA binding
chromatin binding
transcription factor activity, sequence-specific DNA binding
sequence-specific DNA binding
RNA polymerase II sequence-specific DNA binding transcription factor binding
basic leucine zipper transcription factor
negative regulation of transcription from RNA polymerase II promoter
nitrogen catabolite activation of transcription from RNA polymerase II promoter
regulation of transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
autophagy
cellular amino acid biosynthetic process
positive regulation of autophagy
negative regulation of ribosomal protein gene transcription from RNA polymerase II promoter in response to nutrient levels
positive regulation of transcription from RNA polymerase II promoter in response to nitrogen starvation
positive regulation of RNA polymerase II transcriptional preinitiation complex assembly
positive regulation of transcription initiation from RNA polymerase II promoter
positive regulation of cellular response to amino acid starvation
protein localization to nuclear periphery
