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Recommended positive controls: HepG2, NIH-3T3.
Predicted reactivity: Mouse (96%), Rat (97%), Zebrafish (88%), Xenopus laevis (88%), Dog (97%), Rabbit (97%), Sheep (98%), Chimpanzee (100%), Bovine (98%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
GDP dissociation inhibitors are proteins that regulate the GDP-GTP exchange reaction of members of the rab family, small GTP-binding proteins of the ras superfamily, that are involved in vesicular trafficking of molecules between cellular organelles. GDIs slow the rate of dissociation of GDP from rab proteins and release GDP from membrane-bound rabs. GDI1 is expressed primarily in neural and sensory tissues. Mutations in GDI1 have been linked to X-linked nonspecific mental retardation.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: GDI-1; Guanosine diphosphate dissociation inhibitor 1; mental retardation, X-linked 48; Oligophrenin-2; Protein XAP-4; Rab GDI alpha; Rab GDIalpha; Rab GDP dissociation inhibitor alpha; rab GDP-dissociation inhibitor, alpha; RABGD RABGDIA; testis secretory sperm-binding protein Li 208a
基因别名: 1A; GDI1; GDIA; GDIalpha; GDIL; MRX41; MRX48; OPHN2; RABGD1A; RABGDIA; XAP-4; XAP4
UniProt ID: (Human) P31150, (Mouse) P50396
Entrez Gene ID: (Human) 2664, (Mouse) 14567
分子生物学功能: G-protein modulator protein-binding activity modulator