Search
Invitrogen
GEF-H1 Recombinant Rabbit Monoclonal Antibody (K01_3X88)
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
Additional Information:
{{banner.description}}
产品信息
MA567137
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
Expression System
HEK293F
分类
Recombinant Monoclonal
类型
Antibody
克隆号
K01_3X88
抗原
A synthesized peptide derived from human GEF H1.
偶联物
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
Protein A/G
保存液
PBS, pH 7.4, with 50% glycerol, 150mM NaCl, 0.05% BSA
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
靶标信息
GEF-H1 activates Rho GTPases by promoting the exchange of GDP and GTP. Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. GEF-H1 may be involved in epithelial barrier permeability, cell motility and polarization, dendritic spine morphology, antigen presentation, leukemic cell differentiation, cell cycle regulation, innate immune response, and cancer. Alternatively spliced transcript variants encoding different isoforms have been identified.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
篇参考文献 (0)
您是否在文献中引用过该产品？请点击下方按钮邮件告知我们。
生物信息学
蛋白别名: DKFZp547L106; DKFZp547P1516; FLJ45440; GEF-H1; Guanine nucleotide exchange factor H1; LBC'S first cousin; Lymphoid blast crisis-like 1; Microtubule-regulated Rho-GEF; Oncogene LFC; OTTHUMP00000018855; Proliferating cell nucleolar antigen p40; Rho guanine nucleotide exchange factor 2; Rho/Rac guanine nucleotide exchange factor (GEF) 2; Rhobin; unnamed protein product
基因别名: AA408978; ARHGEF2; GEF; GEF-H1; GEFH1; KIAA0651; Lbcl1; Lfc; LFP40; mKIAA0651; NEDMHM; P40
UniProt ID: (Human) Q92974, (Mouse) Q60875, (Rat) Q5FVC2
Entrez Gene ID: (Human) 9181, (Mouse) 16800, (Rat) 310635
cell morphogenesis
immune system process
intracellular protein transport
actin filament organization
negative regulation of microtubule depolymerization
nervous system development
cell differentiation
positive regulation of interleukin-6 production
positive regulation of tumor necrosis factor production
regulation of Rho protein signal transduction
regulation of cell proliferation
innate immune response
positive regulation of neuron differentiation
positive regulation of transcription from RNA polymerase II promoter
positive regulation of peptidyl-tyrosine phosphorylation
regulation of small GTPase mediated signal transduction
positive regulation of NF-kappaB transcription factor activity
cell division
asymmetric neuroblast division
negative regulation of necroptotic process
cellular response to muramyl dipeptide
cellular response to tumor necrosis factor
cellular hyperosmotic response
negative regulation of extrinsic apoptotic signaling pathway via death domain receptors
negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress
positive regulation of neuron migration
establishment of mitotic spindle orientation
cell cycle
mitotic nuclear division
intracellular signal transduction
positive regulation of GTPase activity
negative regulation of neurogenesis
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
