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Positive Samples: Raji, HL-60, U-937, Mouse liver
Immunogen sequence: FTNSYRKVLG QLSARKLLQ
The activated kinase acts on a variety of targets. Likely to be the GTPase effector that links the Rho-related GTPases to the JNK MAP kinase pathway. Activated by CDC42 and RAC1. Involved in dissolution of stress fibers and reorganization of focal complexes. Involved in regulation of microtubule biogenesis through phosphorylation of TBCB. Activity is inhibited in cells undergoing apoptosis, potentially due to binding of CDC2L1 and CDC2L2.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: GHRH; GRF; Growth hormone-releasing factor; Growth hormone-releasing hormone; MGC119781; OTTHUMP00000030915; sermorelin; Somatocrinin; Somatoliberin; Somatorelin
基因别名: GHRF; GHRH; GRF; INN
UniProt ID: (Human) P01286, (Rat) P09916, (Mouse) P16043
Entrez Gene ID: (Human) 2691, (Rat) 29446, (Mouse) 14601